平安！ 发表于 2011-11-9 19:57
! p$ _8 i! d. L4 S0 ePazopanib (100 mg/kg/day free base equivalent)
( [( J3 O8 }& c9 O: Z$ Z' J5 X 这是个已经在美国上市的老药了，能下载到正式药物使用说明书英文版。; O6 G9 p$ [, [
搜索了一下，原料一大堆。
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对不起！100mg/kg是用于移植瘤的，我弄错了。2 R. G/ r$ t6 V) L- o
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以下是正版说明书的推荐用量。! }/ Z" A' a5 I) n( m Y: Q" W
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--------------------- DOSAGE AND ADMINISTRATION ----------------9 M$ T. _+ M' j. R
* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1) ! W, p. m) Y, v% L0 y
* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2) ) ^* p$ g6 c1 U3 r ?; s$ p
---------------------DOSAGE FORMS AND STRENGTHS --------------
* T5 W2 a3 D/ y200 mg tablets. (3)
; M" N/ g+ v* e" S+ @, N1 Z# S-------------------------------CONTRAINDICATIONS------------------------ |
显身卡
