看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯，血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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/ }9 a: {1 v9 {3 B: |; y, XCurrently available feasibility data for possible combination strategies. + L0 B4 o+ f+ U# W6 T6 I$ ^
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Combination Feasibility according to preliminary data 7 ~7 P6 T, r( U1 W3 j. E
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g1 s4 f4 H$ o7 `) EBevacizumab + sorafenib Yes, reduced dose
5 }9 J& K+ c# A' b. {6 F- ]Bevacizumab + sunitinib† No
" r( e( ~8 R5 w8 T N7 Q, `# TBevacizumab + temsirolimus Yes
/ h/ h6 e; P: A* E9 `Bevacizumab + everolimus Yes
) r0 Z8 A6 e, ~0 ~Sorafenib + sunitinib ?
: X; i& u( f \- q+ j1 }: u* GSorafenib + temsirolimus Yes, reduced dose 7 [+ Q0 V/ a: x2 s3 l4 @9 p
Sorafenib + everolimus Yes, reduced dose - z- Q8 Y' v# e0 [; b2 |
Sunitinib + temsirolimus† No $ h8 M3 j* ]9 R' B4 M( N/ @- _
Sunitinib + everolimus ?
' y- Q' S7 _! I7 }/ G0 A6 Z1 TTemsirolimus + everolimus ?
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: _4 t+ P& d/ g! P ^& z( J†Led to US FDA warning.0 |# V& f4 ?$ Q9 a$ [/ V3 Q W5 I
?: As yet unattempted combination.
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